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AMG-517

AMG-517

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Product Code: 3019
Availability: In Stock
$713.00
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AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM.

Chemical Name Acetamide, N-[4-[[6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]-

Inhibitors Others TRPV AMG-517 659730-32-2
Biological Activity:
Biological Activity AMG 517 is a potent and selective TRPV1 antagonist, antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM.
Technical Data:
M.W. 430.4
Formula: C20H13F3N4O2S
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 659730-32-2
References:
References Gavva NR, et al. J Pharmacol Exp Ther, 2007, 323(1), 128-137. Gavva NR, et al. Pain, 2008, 136(1-2), 202-210.

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