PKC Beta Inhibitor

PKC Beta Inhibitor

Product Code: 9785
Availability: In Stock

An anilino-monoindolylmaleimide compound that is a potent inhibitor of PKCβ isozymes.



Chemical Name: PKC Beta Inhibitor

Biological Activity:
Biological Activity PKCβ Inhibitor is an anilino-monoindolylmaleimide compound that acts as a potent and ATP-competitive inhibitor of PKCβ isozymes (IC50 = 5 nM and 21 nM for human PKCβII and βI) and displays greater selectivity over PKCα, PKCγ,PKCε (IC50 = 331 nM, > 1 μM, and 2.8 μM, respectively).
Technical Data:
M.W. 411.46
Formula: C<sub>24</sub>H<sub>21</sub>N<sub>5</sub>O<sub>2</sub>
Solubility: Soluble in DMSO (100 mg/ml).
Storage: Store at 4° C
CAS No: 257879-35-9
References Tanaka, M., et al. 2004. Bioorg. Med. Chem. Lett. 14, 5171. Pubchem ID: 6419755

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