NU7441

NU7441

Product Code: 3346
Availability: In Stock
$146.00
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NU7441 is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM.

Chemical Name 4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-

Biological Activity:
Biological Activity NU7441 is a highly potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 μM.
Technical Data:
M.W. 413.49
Formula: <p>C<sub>25</sub>H<sub>19</sub>NO<sub>3</sub>S</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 503468-95-9
References:
References Leahy JJ, et al. Bioorg Med Chem Lett, 2004, 14(24), 6083-6087. Zhao Y, et al. Cancer Res, 2006 , 66(10), 5354-5362. Tavecchio M, et al. Cancer Chemother Pharmacol, 2012, 69(1), 155-164. Cruet-Hennequart S, et al. DNA Repair (Amst), 2006, 5(4), 491-504. Willmore E, et al. Clin Cancer Res, 2008, 14(12), 3984-3992. Elliott SL, et al. Br J Haematol, 2011, 152(1), 61-71.

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