GSK2334470

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Product Code: 3161
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$180.00

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GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM, with no activity at other close related AGC-kinases.

Chemical Name : 3-Piperidinecarboxamide, 1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-6-methyl-, (3S,6R)-

Biological Activity:
Biological Activity	GSK2334470 is a novel PDK1 inhibitor with IC50 of ~10 nM, with no activity at other close related AGC-kinases.
Technical Data:
M.W.	462.59
Formula:	C<sub>25</sub>H<sub>34</sub>N<sub>8</sub>O
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	1227911-45-6
References:
References	Najafov A, et al. Biochem J, 2011, 433(2), 357-369. Artamonov M, et al. PLoS One, 2013, 8(3), e58703. Raimondi C, et al. J Cell Sci, 2012, 125(Pt 13), 3153-3163.

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