ADX-47273

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Product Code: 3009
Availability: In Stock

$461.00

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ADX47273 is a potent and specific mGlu5 positive allosteric modulator(PAM) with EC50 of 0.17 μM, showing no activity at other mGlu subtypes.

Chemical Name (S)-(4-fluorophenyl)(3-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone

Biological Activity:
Biological Activity	ADX47273 is a potent and specific mGlu5 positive allosteric modulator(PAM) with EC50 of 0.17 μM, showing no activity at other mGlu subtypes.
Technical Data:
M.W.	369.36
Formula:	<p> C<sub>20</sub>H<sub>17</sub>F<sub>2</sub>N<sub>3</sub>O<sub>2</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	851881-60-2
References:
References	Liu F, et al. J Pharmacol Exp Ther, 2008, 327(3), 827-839. Rosenbrock H, et al. Eur J Pharmacol, 2010, 639(1-3), 40-6. Schlumberger C, et al. Pharmacol Biochem Behav, 2010, 95(1), 23-30.

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