Pemetrexed

Pemetrexed

Product Code: 3345
Availability: In Stock
$146.00
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Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.

Chemical Name: sodium (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate

Biological Activity:
Biological Activity Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively.
Technical Data:
M.W. 471.37
Formula: <p>C<sub>20</sub>H<sub>19</sub>N<sub>5</sub>Na<sub>2</sub>O<sub>6</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 150399-23-8
References:
References Shih C, et al. Cancer Res. 1997, 57(6), 1116-1123. Iwahori K, et al. Int J Cancer. 2012, doi: 10.1002/ijc.27611. Teicher BA, et al. Clin Cancer Res. 2000, 6(3), 1016-1023.

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