Roflumilast

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Product Code: 3276
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Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM.

Chemical Name:
3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

Biological Activity:
Biological Activity	Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM.
Technical Data:
M.W.	403.21
Formula:	C<sub>17</sub>H<sub>14</sub>Cl<sub>2</sub>F<sub>2</sub>N<sub>2</sub>O<sub>3</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	162401-32-3
References:
References	Hatzelmann A, et al. Pulm Pharmacol Ther, 2010, 23(4), 235-256. Hatzelmann A, et al. J Pharmacol Exp Ther, 2001, 297(1), 267-279. Martorana PA, et al. BMC Pulm Med, 2008, 8:17. Cortijo J, et al. Br J Pharmacol, 2009, 156(3), 534-544.

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