DAPT

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Product Code: 3110
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DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.

Chemical Name:

(S)-tert-butyl 2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate

Biological Activity:
Biological Activity	DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.
Technical Data:
M.W.	432.46
Formula:	C<sub>23</sub>H<sub>26</sub>F<sub>2</sub>N<sub>2</sub>O<sub>4</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	208255-80-5
References:
References	Dovey HF, et al. J Neurochem. 2001, 76(1), 173-181. Cao H, et al. APMIS. 2012, 120(6), 441-450. Nasoohi S, et al. Neuroscience. 2012, 210, 99-109.

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