Ketoconazole

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Product Code: 3412
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Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively.

Chemical Name 1-(4-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethanone

Biological Activity:
Biological Activity	Ketoconazole inhibits cyclosporine oxidase and testosterone 6 beta-hydroxylase with IC50 of 0.19 mM and 0.22 mM, respectively.
Technical Data:
M.W.	531.43
Formula:	<p>C<sub>26</sub>H<sub>28</sub>Cl<sub>2</sub>N<sub>4</sub>O<sub>4</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	65277-42-1
References:
References	Oliver WR Jr, et al. Proc Natl Acad Sci U S A, 2001, 98(9), 5306-5311. Eil C, et al. Horm Metab Res, 1992, 24(8), 367-370. Forgue-Lafitte ME, et al. Cancer Res, 1992, 52(24), 6827-6831. Gupta AK, et al. Br J Dermatol, 2000, 142(4), 758-765. Goeders NE, et al. Drug Alcohol Depend, 1998, 53(1), 67-77. Salphati L, et al. Pharmacology, 1998, 56(6), 308-313.

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