Abiraterone

Abiraterone

Product Code: 3436
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Abiraterone is a potent CYP17 inhibitor with IC50 of 2 nM.

Chemical name:

(3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol.

 

Biological Activity:
Biological Activity Abiraterone is a potent CYP17 inhibitor with IC50 of 2 nM.
Technical Data:
M.W. 349.51
Formula:

C24H31NO

Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 154229-19-3
References:
References Attard G, et al. J Clin Oncol. 2008, 26(28), 4563-4571. Richards J, et al. Cancer Res. 2012, 72(9), 2176-2182. Duc I, et al. J Steroid Biochem Mol Biol. 2003, 84(5), 537-542. Hu Q, et al. J Med Chem. 2010, 53(15), 5749-5758. Bruno RD, et al. Steroids. 2011, 76(12), 1268-1279. [6] Haidar S, et al. J Steroid Biochem Mol Biol. 2003, 84(5),555-562.

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