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AZD8055

AZD8055

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Product Code: 3046
Availability: In Stock
$146.00
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AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM with excellent selectivity (∼1,000-fold) against PI3K isoforms and ATM/DNA-PK. Phase 1.

Chemical Name: (5-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol

Inhibitors PI3K/Akt/mTOR mTOR AZD8055 1009298-09-2
Biological Activity:
Biological Activity AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM with excellent selectivity (∼1,000-fold) against PI3K isoforms and ATM/DNA-PK. Phase 1.
Technical Data:
M.W. 465.54
Formula: C<sub>25</sub>H<sub>31</sub>N<sub>5</sub>O<sub>4</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 1009298-09-2
References:
References Chresta CM, et al. Cancer Res, 2010, 70(1), 288-298. Willems L, et al. Leukemia, 2011, doi: 10.1038/leu.2011.339. Houghton PJ, et al. Pediatr Blood Cancer, 2012, 58(2), 191-199. García-Martínez JM, et al. Br J Cancer, 2011, 104(7), 1116-1

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