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C646

C646

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Product Code: 3082
Availability: In Stock
$180.00
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C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases.

Chemical Name Benzoic acid, 4-[4-[[5-(4,5-dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]-

Inhibitors Epigenetics Histone Acetyltransferase C646 328968-36-1
Biological Activity:
Biological Activity C646 is an inhibitor for histone acetyltransferase, and inhibits p300 with a Ki of 400 nM. Preferentially selective for p300 versus other acetyltransferases.
Technical Data:
M.W. 445.42
Formula: <p>C<sub>24</sub>H<sub>19</sub>N<sub>3</sub>O<sub>6</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 328968-36-1
References:
References Bowers EM, et al. Chem Biol, 2010, 17(5), 471-482. Santer FR, et al. Mol Cancer Ther, 2011, 10(9), 1644-1655. Crump NT, et al. PNAS, 2011, 108(19), 7814-7819. Marek R, et al. J Neurosci, 2011, 31(20), 7486-7491. Zhu XY, et al. Mol Pain, 2012, 8(84)

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