EX 527

0 reviews Write a review

Product Code: 3141
Availability: In Stock

$95.00

MG Options

Qty

EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3.

Chemical Name (S)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide

Biological Activity:
Biological Activity	EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3.
Technical Data:
M.W.	248.71
Formula:	C<sub>13</sub>H<sub>13</sub>ClN<sub>2</sub>O
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	49843-98-3
References:
References	Solomon JM, et al. Mol Cell Biol, 2006, 26(1), 28-38. Kabra N, et al. J Biol Chem, 2009, 284(27), 18210-18217. Vetterli L, et al. J Biol Chem, 2011, 286(8), 6049-6060. Velásquez DA, et al. Diabetes, 2011, 60(4), 1177-118

Write a review

Your Name

Your Review Note: HTML is not translated!

Rating Bad Good