MK-1775

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Product Code: 3373
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MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM; hinders G2 DNA damage checkpoint. Phase 2.

Chemical Name 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one

Biological Activity:
Biological Activity	MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM; hinders G2 DNA damage checkpoint. Phase 2.
Technical Data:
M.W.	500.6
Formula:	<p>C<sub>27</sub>H<sub>32</sub>N<sub>8</sub>O<sub>2</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	955365-80-7
References:
References	Hirai H, et al. Mol Cancer Ther, 2009, 8(11), 2992-3000.

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MK-1775

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