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Daclatasvir (BMS-790052)

Daclatasvir (BMS-790052)

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Product Code: 3107
Availability: In Stock
$398.00
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BMS-790052 is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.

Chemical Name

Carbamic acid, N,N'-[[1,1'-biphenyl]-4,4'-diylbis[1H-imidazole-5,2-diyl-(2S)-2,1-pyrrolidinediyl[(1S)-1-(1-methylethyl)-2-oxo-2,1-ethanediyl]]]bis-, C,C'-dimethyl ester

Inhibitors Microbiology HCV Protease Daclatasvir (BMS-790052) 1009119-64-5
Biological Activity:
Biological Activity BMS-790052 is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.
Technical Data:
M.W. 738.88
Formula: C<sub>40</sub>H<sub>50</sub>N<sub>8</sub>O<sub>6</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 1009119-64-5
References:
References Gao M, et al. Nature, 2010, 465(7294), 96-100. Lee C, et al. Virology, 2011, 414(1), 10-18. Wang C, et al. Antimicrob Agents Chemother, 2012, 56(3), 1588-1590. O'Boyle DR 2nd, et al. Antimicrob Agents Chemother, 2005, 49(4), 1346-1353.

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