Sotrastaurin

0 reviews Write a review

Product Code: 3244
Availability: In Stock

$839.00

MG Options

Qty

Sotrastaurin is a potent and selective pan-PKC inhibitor, mostly for PKCθ with K_i of 0.22 nM; inactive to PKCζ. Phase 1/2.

Chemical Name:
3-(1H-indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)-1H-pyrrole-2,5-dione

Biological Activity:
Biological Activity	Sotrastaurin is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM; inactive to PKCζ. Phase 1/2.
Technical Data:
M.W.	438.48
Formula:	C<sub>25</sub>H<sub>22</sub>N<sub>6</sub>O<sub>2</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	425637-18-9
References:
References	Evenou JP, et al. J Pharmacol Exp Ther, 2009, 330(3), 792-801. Naylor TL, et al. Cancer Res, 2011, 71(7), 2643-2653. Weckbecker G, et al. Transpl Int, 2010, 23(5), 543-552.

Write a review

Your Name

Your Review Note: HTML is not translated!

Rating Bad Good