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Birinapant

Birinapant

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Product Code: 3068
Availability: In Stock
$2,137.00
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Birinapant is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP. Phase 1/2.

Chemical Name: Propanamide, N,N'-[(6,6'-difluoro[2,2'-bi-1H-indole]-3,3'-diyl)bis[methylene[(2R,4S)-4-hydroxy-2,1-pyrrolidinediyl][(1S)-1-ethyl-2-oxo-2,1-ethanediyl]]]bis[2-(methylamino)-, (2S,2'S)-

Inhibitors Apoptosis IAP Birinapant 1260251-31-7
Biological Activity:
Biological Activity Birinapant is a SMAC mimetic antagonist, mostly to cIAP1 with Kd of <1 nM, less potent to XIAP. Phase 1/2.
Technical Data:
M.W. 806.94
Formula: C<sub>42</sub>H<sub>56</sub>F<sub>2</sub>N<sub>8</sub>O<sub>6</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 1260251-31-7
References:
References Allensworth JL, et al. Breast Cancer Res Treat, 2013, 137(2), 359-371. Krepler C, et al. Clin Cancer Res, 2013, 19(7), 1784-1794.

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