Dasatinib

Dasatinib

Product Code: 3111
Availability: In Stock
$180.00
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Dasatinib is a novel, potent and multi-targeted inhibitor that targets AblSrc and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.

Chemical Name:

N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide

Biological Activity:
Biological Activity Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively.
Technical Data:
M.W. 488.01
Formula: C<sub>22</sub>H<sub>26</sub>ClN<sub>7</sub>O<sub>2</sub>S
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 302962-49-8
References:
References O'Hare T, et al. Cancer Res. 2005, 65(11), 4500-4505. Shah NP, et al. Blood, 2006, 108(1), 286-291. [Chan CM, et al. Clin Cancer Res. 2012, 18(13), 3580-3591. Dargart JL, et al. Antiviral Res. 2012, 95(1), 49-56.

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