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TG101348

TG101348

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Product Code: 3223
Availability: In Stock
$209.00
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TG-101348 (SAR302503) is a selective inhibitor of JAK2 with IC50 of 3 nM, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Phase 1/2.

Chemical Name:
N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide

Inhibitors MStem Cells & Wnt JAK TG101348 TG101348 936091-26-8
Biological Activity:
Biological Activity TG-101348 (SAR302503) is a selective inhibitor of JAK2 with IC50 of 3 nM, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3. Phase 1/2.
Technical Data:
M.W. 524.68
Formula: C<sub>27</sub>H<sub>36</sub>N<sub>6</sub>O<sub>3</sub>S
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 936091-26-8
References:
References Wernig G, et al. Cancer Cell, 2008, 13(4), 311-320. Geron I, et al. Cancer Cell, 2008, 13(4), 321-330. Lasho T, et al. Leukemia, 2010, 24(7), 1378-1380.

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