Elvitegravir (GS-9137, JTK-303)

Elvitegravir (GS-9137, JTK-303)

Product Code: 3126
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Elvitegravir (EVG, JTK-303/GS-9137) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.

Chemical Name

(S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Biological Activity:
Biological Activity Elvitegravir (EVG, JTK-303/GS-9137) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.
Technical Data:
M.W. 447.88
Formula: C23H23ClFNO5
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 697761-98-1
References:
References Shimura K, et al. J Virol. 2008, 82(2), 764-774. Lampiris HW. Expert Rev Anti Infect Ther. 2012, 10(1), 13-20.

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