Erlotinib HCl

0 reviews Write a review

Product Code: 3137
Availability: In Stock

$180.00

MG Options

Qty

Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Phase 3.

Chemical Name :N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride

Biological Activity:
Biological Activity	Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Phase 3.
Technical Data:
M.W.	429.90
Formula:	C<sub>22</sub>H<sub>23</sub>N<sub>3</sub>O<sub>4</sub>.HCl
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	183319-69-9
References:
References	Moyer JD, et al. Cancer Res. 1997, 57(21), 4838-4848. Li T, et al. Clin Cancer Res, 2007, 13(11), 3413-3422. Ali S, et al. Mol Cancer Ther, 2008, 7(6), 1708-1719. Buck E, et al. Mol Cancer Ther. 2006, 5(11), 2676-2784. Higgins B, et al. Anticancer Drugs. 2004, (5), 503-512. Furugaki K,et al. Oncol Lett. 2010, 1(2), 231-235. Bago-Horvath Z, et al. 2012, DOI: 10.1159/000337257

Write a review

Your Name

Your Review Note: HTML is not translated!

Rating Bad Good