Bleomycin Sulfate is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells.
Chemcial name: 3-[[2-[2-[2-[[2-[[(2S,3S,4R)-4-[[(2R,3S)-3-[(2S,3S,4R,5S,6R)-3-[(2S,3S,4R,5S,6R)-4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-3-(1H-imidazol-4-yl)-2-[[2-(propylaminomethyl)pyrimidine-4-carbonyl]amino]propanoyl]amino]-3-hydroxy-2-methyl-pentanoyl]amino]-3-hydroxy-butanoyl]amino]ethyl]thiazol-4-yl]thiazole-5-carbonyl]amino]propyl-dimethyl-sulfonium; Bleomycine Sulfate
Biological Activity: |
Biological Activity |
Bleomycin Sulfate is a glycopeptide antibiotic and an anticancer agent for squamous cell carcinomas (SCC) with IC50 of 4 nM in UT-SCC-19A cells. |
Technical Data: |
M.W. |
1512.62 |
Formula: |
<p>C<sub>55</sub>H<sub>85</sub>N<sub>17</sub>O<sub>25</sub>S<sub>4</sub></p>
|
Solubility: |
DMSO |
Purity: |
98% |
Storage: |
-20℃ |
CAS No: |
9041-93-4 |
References: |
References |
Jääskelä-Saari HA, et al. Acta Otolaryngol Suppl. 1997, 529, 241-244.
Denholm EM, et al. Am J Pathol. 1989, 134(2), 355-363.
Cort A, et al. Mol Med Report. 2012, 5(6), 1481-1486.
Paviolo NS, et al. Mutat Res. 2012, 734(1-2), 5-11.
Banerjee ER, et al. Stem Cell Res Ther. 2012, 3(3), 21.
Danesi CC, et al. Mutat Res. 2012. |