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Gemcitabine HCl

Gemcitabine HCl

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Product Code: 3155
Availability: In Stock
$83.00
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Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.

 

Chemical Name : 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one hydrochloride

Inhibitors DNA Damage DNA/RNA Synthesis Gemcitabine HCl 122111-03-9
Biological Activity:
Biological Activity Gemcitabine HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
Technical Data:
M.W. 299.66
Formula: C<sub>9</sub>H<sub>11</sub>F<sub>2</sub>N<sub>3</sub>O<sub>4.</sub>HCI
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 122111-03-9
References:
References Shi X, et al. Oncology. 2002, 62(4), 354-362. Holcomb BK, et al. J Gastrointest Surg. 2012. Hou J, et al. PLoS One. 2012, 7(5), e36252.

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