Vorinostat

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Product Code: 3186
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Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM.

Chemical Name:
2-[[3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl]amino]benzoic acid

Biological Activity:
Biological Activity	Vorinostat (suberoylanilide hydroxamic acid, SAHA) is an HDAC inhibitor with IC50 of ~10 nM.
Technical Data:
M.W.	264.3
Formula:	C<sub>14</sub>H<sub>20</sub>N<sub>2</sub>O<sub>3</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	149647-78-9
References:
References	Richon VM, et al. Proc Natl Acad Sci U S A, 1998, 95(6), 3003-3007. Butler LM, et al. Cancer Res, 2000, 60(18), 5165-5170. Munster PN, et al. Cancer Res, 2001, 61(23), 8492-8497. Hockly E, et al. Natl Acad Sci U S A, 2003, 100(4), 2041-2046. Mitsiades CS, et al. Proc Natl Acad Sci U S A, 2004, 101(2), 540-545. Pei XY, et al. Clin Cancer Res, 2004, 10(11), 3839-3852. Zhang G, et al. Clin Cancer Res, 2008, 14(17), 5385-5399. Dai Y, et al. Blood, 2008, 112(3), 793-804.

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