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Volasertib

Volasertib

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Product Code: 3187
Availability: In Stock
$259.00
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BI6727 (Volasertib) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM. It shows 6- and 65-fold greater selectivity against Plk2 and Plk3. Phase 2.

Chemical Name:
N-((1r,4r)-4-(4-(cyclopropylmethyl)piperazin-1-yl)cyclohexyl)-4-((R)-7-ethyl-8-isopropyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-ylamino)-3-methoxybenzamide
 

Inhibitors Cell Cycle PLK Volasertib 755038-65-4
Synonym
Synonym Inhibitors , Cell Cycle , PLK ,Volasertib ,755038-65-4
Biological Activity:
Biological Activity BI6727 (Volasertib) is a highly potent Plk1 inhibitor with IC50 of 0.87 nM. It shows 6- and 65-fold greater selectivity against Plk2 and Plk3. Phase 2.
Technical Data:
M.W. 618.81
Formula: C<sub>34</sub>H<sub>50</sub>N<sub>8</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 755038-65-4
References:
References Rudolph D, et al. Clin Cancer Res, 2009, 15(9), 3094-3102. Grinshtein N, et al. Cancer Res, 2011, 71(4), 1385-1395. Harris PS, et al. BMC Cancer, 2012, 12, 80.

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