MK-8776

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Product Code: 3375
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$461.00

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SCH 900776 is a selective Chk1 inhibitor with IC50 of 3 nM. It shows 500-fold selectivity against Chk2. Phase 2.

Chemical Name 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-((R)-piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine

Biological Activity:
Biological Activity	SCH 900776 is a selective Chk1 inhibitor with IC50 of 3 nM. It shows 500-fold selectivity against Chk2. Phase 2.
Technical Data:
M.W.	376.25
Formula:	<p>C<sub>15</sub>H<sub>18</sub>BrN<sub>7</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	891494-63-6
References:
References	Guzi TJ, et al. Mol Cancer Ther, 2011, 10(4), 591-602. Montano R, et al. Mol Cancer Ther, 2012, 11(2), 427-438. Schenk EL, et al. Clin Cancer Res, 2012, 18(19), 5364-5373.

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