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SB743921

SB743921

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Product Code: 3252
Availability: In Stock
$398.00
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SB743921 is a kinesin spindle protein (KSP) inhibitor with Ki of 0.1 nM, almost no affinity to MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4 and CENP-E. Phase 1/2.

Chemical Name:
R)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl)-4-methylbenzamide hydrochloride

Inhibitors Cytoskeletal Signaling Kinesin SB743921 940929-33-9
Biological Activity:
Biological Activity SB743921 is a kinesin spindle protein (KSP) inhibitor with Ki of 0.1 nM, almost no affinity to MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4 and CENP-E. Phase 1/2.
Technical Data:
M.W. 553.52
Formula: C<sub>31</sub>H<sub>33</sub>N<sub>2</sub>O<sub>3</sub>.HCl
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 940929-33-9
References:
References Jackson JR, et al. AACR, 2006, Abst 0906. Sakowicz R, et al. Cancer Res, 2004, 64(9), 3276-3280.

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