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Enzastaurin

Enzastaurin

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Product Code: 3135
Availability: In Stock
$146.00
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Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3.

Chemical Name 3-(1-methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione

Inhibitors Cytoskeletal Signaling PKC Enzastaurin 170364-57-5
Biological Activity:
Biological Activity Enzastaurin (LY317615) is a potent PKCβ selective inhibitor with IC50 of 6 nM, 6- to 20-fold selectivity against PKCα, PKCγ and PKCε. Phase 3.
Technical Data:
M.W. 515.61
Formula: C<sub>32</sub>H<sub>29</sub>N<sub>5</sub>O<sub>2</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 170364-57-5
References:
References Graff JR, et al. Cancer Res, 2005, 65(16), 7462-7469. Rovedo MA, et al. J Invest Dermatol, 2011, 131(7), 1442-1449. Podar K, et al. Blood, 2007, 109(4), 1669-1677.

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