Perifosine

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Product Code: 3341
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Perifosine (KRX-0401) is a novel Akt inhibitor with IC50 of 4.7 μM, targets pleckstrin homology domain of Akt. Phase 2.

Chemical Name Piperidinium, 4-[[hydroxy(octadecyloxy)phosphinyl]oxy]-1,1-dimethyl-, inner salt

Biological Activity:
Biological Activity	Perifosine (KRX-0401) is a novel Akt inhibitor with IC50 of 4.7 μM, targets pleckstrin homology domain of Akt. Phase 2.
Technical Data:
M.W.	461.66
Formula:	<p>C<sub>25</sub>H<sub>52</sub>NO<sub>4</sub>P</p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	157716-52-4
References:
References	Vyomesh Patel, et al. Cancer Res, 2002, 62(5), 1401-1409 Momota H, et al. Cancer Res, 2005, 65(16), 7429-7435. Hideshima T, et al. Blood, 2006, 107(10), 4053-4062. Fei HR, et al. Cytotechnology, 2010, 62(5), 449-460 Catley L, et al. Exp Hematol, 2007, 32(7), 1038-1046

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