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Sorafenib Tosylate

Sorafenib Tosylate

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Product Code: 3246
Availability: In Stock
$272.00
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Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.

Chemical Name:
2-Pyridinecarboxamide, 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-, 4-methylbenzenesulfonate (1:1)

Inhibitors MAPK Raf Sorafenib Tosylate 3246
Biological Activity:
Biological Activity Sorafenib Tosylate (Bay 43-9006) is a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively.
Technical Data:
M.W. 637.03
Formula: C<sub>21</sub>H<sub>16</sub>ClF<sub>3</sub>N<sub>4</sub>O<sub>3</sub>.C<sub>7</sub>H<sub>8</sub>O<sub>3</sub>S
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 475207-59-1
References:
References Wilhelm SM, et al. Cancer Res, 2004, 64(19), 7099-7109. Liu L, et al. Cancer Res, 2006, 66(24), 11851-11858. Ricci MS, et al. Cancer Cell, 2007, 12(1), 66-80.

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