Vemurafenib

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Product Code: 3191
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Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-Raf^V600E with IC50 of 31 nM.

Chemical Name:
2-[(1-Methylpropyl)dithio]-1H-imidazole

Biological Activity:
Biological Activity	Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.
Technical Data:
M.W.	489.92
Formula:	C<sub>23</sub>H<sub>18</sub>ClF<sub>2</sub>N<sub>3</sub>O<sub>3</sub>S
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	918504-65-1
References:
References	Bollag G, et al. Nature, 2010, 467(7315), 596-599. Yang H, et al. Cancer Res, 2010, 70(13), 5518-5527. Prahallad A, et al. Nature, 2012, 483(7387), 100-103. Kumar A, et al. J Mol Biol, 2005, 348(1), 183-193. Yang H, et al. Cancer Res, 2012, 72(3), 779-789.

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