Lenalidomide

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Product Code: 3400
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Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM.

Chemical Name: 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione

Biological Activity:
Biological Activity	Lenalidomide (CC-5013) is a TNF-α secretion inhibitor with IC50 of 13 nM.
Technical Data:
M.W.	259.26
Formula:	<p>C<sub>13</sub>H<sub>13</sub>N<sub>3</sub>O<sub>3</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	191732-72-6
References:
References	Muller GW, et al. Bioorg Med Chem Lett, 1999, 9(11), 1625-1630. Zangari M, et al. Expert Opin Investig Drugs. 2005, 14(11), 1411-1418. Lopez-Girona A, et al. Leukemia. 2012. Ramsay AG, et al. Blood, 2012, 120(7), 1412-1421. Dredge K, et al. Microvasc Res. 2005, 69(1-2), 56-63. Henry JY, et al. Prostate. 2012, 72(8), 856-867. Ocio EM, et al. Haematologica, 2010, 95(5), 794-803. Henry JY, et al. J Clin Oncol, 2010, 28(suppl), Abst e13155. Moros A, et al. Canc Res, 2012, 72(8, Suppl 1), Abst 1942.

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