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Obatoclax Mesylate

Obatoclax Mesylate

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Product Code: 3329
Availability: In Stock
$398.00
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Obatoclax (GX15-070) is an antagonist of Bcl-2 with Ki of 0.22 μM, can assist in overcoming MCL-1 mediated resistance to apoptosis. Phase 1/2.

Chemical Name (Z)-2-(5-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-4-methoxy-5H-pyrrol-2-yl)-1H-indole mesylate

Inhibitors Apoptosis Bcl-2 Obatoclax (GX15-070) 803712-79-0
Biological Activity:
Biological Activity Obatoclax (GX15-070) is an antagonist of Bcl-2 with Ki of 0.22 μM, can assist in overcoming MCL-1 mediated resistance to apoptosis. Phase 1/2.
Technical Data:
M.W. 413.49
Formula: <p>C<sub>20</sub>H<sub>19</sub>N<sub>3</sub>O.CH<sub>4</sub>O<sub>3</sub>S</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 803712-79-0
References:
References Nguyen M, et al. Proc Natl Acad Sci, 2007, 104(49), 19512-191517. Trudel S, et al. Blood, 2009, 113(2), 299-305. Huang S, et al. Clin Cancer Res, 2009, 15 (1), 150-159. Naim M, et al. J Chem Inf Model, 2007, 47(1), 122-133.

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