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GSK1838705A

GSK1838705A

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Product Code: 3161
Availability: In Stock
$398.00
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GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR and ALK with IC50 of 1.6 nM and 0.5 nM, respectively, and little activity to other protein kinases.

 

Chemical Name : 2-(2-(1-(2-(dimethylamino)acetyl)-5-methoxyindolin-6-ylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-6-fluoro-N-methylbenzamide

Inhibitors Protein Tyrosine Kinase ALKGSK1838705A 1116235-97-2
Biological Activity:
Biological Activity GSK1838705A is a potent IGF-1R inhibitor with IC50 of 2.0 nM, modestly potent to IR and ALK with IC50 of 1.6 nM and 0.5 nM, respectively, and little activity to other protein kinases.
Technical Data:
M.W. 532.57
Formula: C<sub>27</sub>H<sub>29</sub>FN<sub>8</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 1116235-97-2
References:
References Sabbatini P, et al. Mol Cancer Ther. 2009, 8(10), 2811-2820.

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