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Alectinib

Alectinib

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Product Code: 3010
Availability: In Stock
$335.00
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CH5424802 is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429. Phase 1/2.

Chemical Name 9-ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

Inhibitors Angiogenesis ALK Alectinib 1256580-46-7
Biological Activity:
Biological Activity CH5424802 is a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation and higher selectivity for ALK than PF-02341066, NVP-TAE684 and PHA-E429. Phase 1/2.
Technical Data:
M.W. 482.62
Formula: <p>&nbsp;C<sub>30</sub>H<sub>34</sub>N<sub>4</sub>O2</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 1256580-46-7
References:
References Sakamoto H, et al. Cancer Cell. 2011, 19(5), 679-690. Kinoshita K, et al. Bioorg Med Chem. 2012, 20(3), 1271-1280.

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