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AZD4547

AZD4547

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Product Code: 3044
Availability: In Stock
$209.00
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AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 1/2.

Chemical Name: N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide

Inhibitors Protein Tyrosine Kinase FGFR AZD4547 1035270-39-3
Biological Activity:
Biological Activity AZD4547 is a novel selective FGFR inhibitor targeting FGFR1/2/3 with IC50 of 0.2 nM/2.5 nM/1.8 nM, weaker activity against FGFR4, VEGFR2(KDR), and little activity observed against IGFR, CDK2, and p38. Phase 1/2.
Technical Data:
M.W. 463.57
Formula: C<sub>26</sub>H<sub>33</sub>N<sub>5</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 1035270-39-3
References:
References Gavine PR, et al. Cancer Res, 2012, 72(8), 2045-2056.

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