Wishlist (0)
Welcome visitor Login or Register.
My Cart    0 $0.00
Your shopping cart is empty!
BGJ398

BGJ398

0 reviews Write a review
Product Code: 3060
Availability: In Stock
$209.00
-+

BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.

Chemical Name: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)-1-methylurea

Inhibitors Protein Tyrosine Kinase FGFR BGJ398 872511-34-7
Biological Activity:
Biological Activity BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.
Technical Data:
M.W. 560.48
Formula: C<sub>26</sub>H<sub>31</sub>Cl<sub>2</sub>N<sub>7</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 872511-34-7
References:
References Guagnano V, et al. J Med Chem. 2011, 54(20), 7066-7083.

Write a review

Note: HTML is not translated!
    Bad           Good
Continue

About HDH PHARMA

At HDH Pharma, we are committed to offering our clients the highest quality research services with the most convenient and effective communications from both US and Indian operations. Clients in the Americas and Europe can pick up the phone and speak directly with our scientists in the US. Clients in Asia can receive the same rapid response from our scientists in India. HDH’s hybrid operation is designed with our client’s operational needs in mind.


Information

Extras

My Account

Powered By Nsoft Solutions
HDH PHARMA © 2024