Compound 56

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Product Code: 9792
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A potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor.

Chemical Name: 4-[(3-Bromophenyl)amino]-6,7-diethoxyquinazoline

Biological Activity:
Biological Activity	Compound 56 is the most potent and specific inhibitor of the tyrosine kinase activity of the EGFR (epidermal growth factor receptor) (IC50 = 6 pM).
Technical Data:
M.W.	388.3
Formula:	C<sub>18</sub>H<sub>18</sub>BrN<sub>3</sub>O<sub>2</sub>
Solubility:	Soluble in DMSO (200 mg/ml).
Storage:	Store at -20° C
CAS No:	171745-13-4
References:
References	1. Bridges, A.J., et al. 1996. J. Med. Chem. 39: 267-276. PMID: 8568816

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Compound 56

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