Afatinib

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Product Code: 9525
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Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2.

Biological Activity:
Biological Activity	Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Technical Data:
M.W.	485.94
Formula:	C24H25ClFN5O3
Solubility:	100mg/mL in DMSO, 15mg/mL in Ethanol.
Purity:	>99%
Storage:	Store at -20℃.
CAS No:	439081-18-2
References:
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At HDH Pharma, we are committed to offering our clients the highest quality research services with the most convenient and effective communications from both US and Indian operations. Clients in the Americas and Europe can pick up the phone and speak directly with our scientists in the US. Clients in Asia can receive the same rapid response from our scientists in India. HDH’s hybrid operation is designed with our client’s operational needs in mind.

Afatinib

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