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KU-60019

KU-60019

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Product Code: 3404
Availability: In Stock
$183.00
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KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM, 270- and 1600-fold more selective for ATM than DNA-PK and ATR,and is a highly effective radiosensitizer.

Chemical Name: 2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide

Inhibitors DNA Damage ATM/ATR KU-60019 925701-49-1
Biological Activity:
Biological Activity KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM, 270- and 1600-fold more selective for ATM than DNA-PK and ATR,and is a highly effective radiosensitizer.
Technical Data:
M.W. 547.67
Formula: <p>C<sub>30</sub>H<sub>33</sub>N<sub>3</sub>O<sub>5</sub>S</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 925701-49-1
References:
References Golding SE, et al. Mol Cancer Ther, 2009, 8(10), 2894-2902. Clin Cancer Res. 2013, 19(12), 3189-3200.

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