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GSK690693

GSK690693

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Product Code: 3164
Availability: In Stock
$205.00
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GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.

 

Chemical Name : 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-((S)-piperidin-3-ylmethoxy)-1H-imidazo[4,5-c]pyridin-4-yl)-2-methylbut-3-yn-2-ol

Inhibitors PI3K/Akt/mTOR Akt GSK690693 937174-76-0
Biological Activity:
Biological Activity GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
Technical Data:
M.W. 425.48
Formula: C<sub>21</sub>H<sub>27</sub>N<sub>7</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 937174-76-0
References:
References Rhodes N, et al. Cancer Res, 2008, 68(7), 2366-2374. Levy DS, et al. Blood, 2009, 113(8), 1723-1729. Altomare DA, et al. Clin Cancer Res, 2010, 16(2), 486-496.

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