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LY294112

LY294112

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Product Code: 3387
Availability: In Stock
$180.00
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LY294002 is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.

Chemical Name: 2-​(4-​morpholinyl)-​8-​phenyl-​4H-​1-​benzopyran-​4-​one

Inhibitors PI3K/Akt/mTOR PI3K LY294002 154447-36-6
Biological Activity:
Biological Activity LY294002 is the first synthetic molecule known to inhibit PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM, respectively; more stable in solution than Wortmannin, and also blocks autophagosome formation.
Technical Data:
M.W. 307.34
Formula: <p>C<sub>19</sub>H<sub>17</sub>NO<sub>3</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 154447-36-6
References:
References Chaussade C, et al. Biochem J, 2007, 404(3), 449-58. Semba S, et al. Clin Cancer Res, 2002, 8(6), 1957-63. Hu L, et al. Clin Cancer Res, 2000, 6(3), 880-6. Gharbi SI, et al. Biochem J, 2007, 404(1), 15-21.

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