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XL335

XL335

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Product Code: 3180
Availability: In Stock
$398.00
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XL335 is a potent, selective FXR agonist with EC50 of 4 nM, highly selective versus other nuclear receptors, such as LXR, PPAR, ER and etc. Phase 1.

Chemical Name:
5-(2-Chlorophenyl)-7-fluoro-1,2-dihydro-8-methoxy-3-methylpyrazolo[3,4-b][1,4]benzodiazepine

Inhibitors Others FXR XL335 629664-81-9
Biological Activity:
Biological Activity XL335 is a potent, selective FXR agonist with EC50 of 4 nM, highly selective versus other nuclear receptors, such as LXR, PPAR, ER and etc. Phase 1.
Technical Data:
M.W. 438.47
Formula: C<sub>25</sub>H<sub>24</sub>F<sub>2</sub>N<sub>2</sub>O<sub>3</sub>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 629664-81-9
References:
References Flatt B, et al. J Med Chem, 2009, 52(4), 904-907. Zhang S, et al. J Hepatol, 2009, 51(2), 380-388. Zhang S, et al. Biochem Biophys Res Commun, 2009, 379(2), 476-479. Hartman HB, et al. J Lipid Res, 2009, 50(6), 1090-1100.

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