Evacetrapib (LY2484595)

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Product Code: 3140
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Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.

Chemical Name Cyclohexanecarboxylic acid, 4-[[(5S)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl](2-methyl-2H-tetrazol-5-yl)amino]-2,3,4,5-tetrahydro-7,9-dimethyl-1H-1-benzazepin-1-yl]methyl]-, trans-

Biological Activity:
Biological Activity	Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
Technical Data:
M.W.	638.65
Formula:	C<sub>31</sub>H<sub>36</sub>F<sub>6</sub>N<sub>6</sub>O<sub>2</sub>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	1186486-62-3
References:
References	Cao G, et al. J Lipid Res, 2011, 52(12), 2169-2176.

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Evacetrapib (LY2484595)

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