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FK866 (APO866, Daporinad)

FK866 (APO866, Daporinad)

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Product Code: 3395
Availability: In Stock
$209.00
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APO866 effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 of 0.09 nM.

Chemical Name (E)-N-(4-(1-benzoylpiperidin-4-yl)butyl)-3-(pyridin-3-yl)acrylamide

Inhibitors Metabolism Transferase FK866 (APO866 Daporinad) 658084-64-1
Biological Activity:
Biological Activity APO866 effectively inhibits nicotinamide phosphoribosyltransferase (NMPRTase) with IC50 of 0.09 nM. Phase 1/2.
Technical Data:
M.W. 391.51
Formula: <p>C<sub>24</sub>H<sub>29</sub>N<sub>3</sub>O<sub>2</sub></p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 658084-64-1
References:
References Nahimana A, et al. Blood, 2009, 113(14), 3276-3286. Evans L, et al. Arthritis Rheum, 2011, 63(7), 1866-1877. Olesen UH, et al. Mol Cancer Ther, 2010, 9(6), 1609-1617. Zoppoli G, et al. Exp Hematol, 2010, 38(11), 979-988.

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