Pralatrexate

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Product Code: 3300
Availability: In Stock

$398.00

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Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.

Chemical name: N-(4-{1-[(2,4-diaminopteridin-6-yl)methyl]but-3-yn-1-yl}benzoyl)-L-glutamic acid

Biological Activity:
Biological Activity	Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog. It acts as an inhibitor of dihydrofolate reductase. It is selective for the reduced folate carrier type 1. Its IC50 is < 300 nM in some cell lines.
Technical Data:
M.W.	477.47
Formula:	<p>C<sub>23</sub>H<sub>23</sub>N<sub>7</sub>O<sub>5</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	146464-95-1Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog. It acts as an inhibitor of dihydrofolate reductase. It is selective for the reduced folate carrier type 1. Its IC50 is < 300 nM in some cell lines.

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