Plerixafor 8HCl

Plerixafor 8HCl

Product Code: 3306
Availability: In Stock
$108.00
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Plerixafor 8HCl (AMD3100 8HCl) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 andCXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.

Chemical Name 1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8)

Biological Activity:
Biological Activity Plerixafor 8HCl (AMD3100 8HCl) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.
Technical Data:
M.W. 794.47
Formula: <p>C<sub>28</sub>H<sub>54</sub>N<sub>8</sub>.8HCl</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 155148-31-5
References:
References Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211. Fricker SP, et al. Biochem Pharmacol. 2006, 72(5), 588-596. Nishimura Y, et al. J Invest Dermatol. 2012, 132(3 Pt 1), 711-720. Kumar S, et al. Bone, 2012, 50(4), 1012-1018.

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