NPS-2143

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Product Code: 3344
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NPS 2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.

Chemical Name (R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)propan-2-ylamino)propoxy)benzonitrile

Biological Activity:
Biological Activity	NPS 2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.
Technical Data:
M.W.	408.92
Formula:	<p>C<sub>24</sub>H<sub>25</sub>ClN<sub>2</sub>O<sub>2</sub></p>
Solubility:	DMSO
Purity:	98%
Storage:	-20℃
CAS No:	284035-33-2
References:
References	Nemeth EF, et al. J Pharmacol Exp Ther. 2001, 299(1), 323-331. Rybczynska A, et al. J Endocrinol. 2006, 191(1), 189-195. Ohsu T, et al. J Biol Chem. 2010, 285(2), 1016-1022. Nakajima S, et al. Mol Nutr Food Res. 2012, 56(5), 753-760.

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