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SB408124

SB408124

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Product Code: 3261
Availability: In Stock
$146.00
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SB408124 (Tocris-1963) is a non-peptide antagonist forOX1 receptor with Ki of 57 nM and27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.

Chemical Name:
2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid
 

Inhibitors Neuronal Signaling OX Receptor SB408124 288150-92-5
Biological Activity:
Biological Activity SB408124 (Tocris-1963) is a non-peptide antagonist for OX1 receptor with Ki of 57 nM and27 nM in both whole cell and membrane, respectively, exhibits 50-fold selectivity over OX2 receptor.
Technical Data:
M.W. 356.37
Formula: C<sub>19</sub>H<sub>18</sub>F<sub>2</sub>N<sub>4</sub>O
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 288150-92-5
References:
References Langmead CJ, et al, Br J Pharmacol, 2004, 141(2) , 340-346. Woldan-Tambor A, et al, Pharmacol Rep, 2011, 63(3), 717-723. [Kis Gk, et al, Pflugers Arch, 2012, 463(4), 531-536 Yi CX, et al, Diabetes, 2009, 58(9), 1998-2005.

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