Ki16425

Ki16425

Product Code: 3409
Availability: In Stock
$209.00
-+

Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6.

Chemical Name 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-methylisoxazol-5-yl)benzylthio)propanoic acid

Biological Activity:
Biological Activity Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6.
Technical Data:
M.W. 474.96
Formula: <p>C<sub>23</sub>H<sub>23</sub>ClN<sub>2</sub>O<sub>5</sub>S</p>
Solubility: DMSO
Purity: 98%
Storage: -20℃
CAS No: 355025-24-0
References:
References Ohta H, et al, Mol Pharmacol, 2003, 64(4), 994-1005. Moughal NA, et al. J Neurochem, 2006, 98(6), 1920-1929. Nochi H, et al. J Immunol, 2008, 181(7), 5111-5119. Ma L, et al. J Neurochem, 2009, 109(2), 603-610.

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